2023 IN OSLO
Program
16thbis International Wolfsberg Meeting on
Molecular Radiation Biology/Oncology
Hurdalsjøen Hotel, Norway
June 17-19, 2023
Organizers:
Ludwig Dubois (NL)
Heidi Lyng (NO)
Martin Pruschy (CH)
Randi Syljuåsen (NO)
15:00
Opening and Welcome Address
Ludwig Dubois (NL, Maastricht), Heidi Lyng (NO, Oslo), Martin Pruschy (CH, Zurich) & Randi Syljuåsen (NO, Oslo)
15:15 - 16:15
Opening Keynote Lecture
Chairs: Randi Syljuåsen & Bhawna Singh
Scott Lowe, New York, USA
Understanding and exploiting tumor suppressor gene networks
Session 1
Topic 1: DNA repair
Chairs: Randi Syljuåsen & Bhawna Singh
16:15 - 16:45
Invited Lecture
Alessandro A. Sartori, Zurich, CH
Targeting DSB repair in cancer: Hopes and Pitfalls
16:45 - 18:45
Coffe break /
Poster Session Topic 1 (Poster numbers PI.1-PI.20)
18:45 - 19:45
Proffered Paper Talks
.
18:45 - 19:05
Marcel van Vugt, Groningen, NL
Determinants of inflammatory signaling in genomically instable cancers
19:05 - 19:25
Helga B. Landsverk, Oslo, NO
The RNA polymerase II C-terminal domain promotes non-homologous end-joining
19:25 - 19:45
Sunil J Advani, San Diego, US
Spatially precise radio-chemo-immunotherapy using antibody drug conjugate targeted radiosensitizers
20:00
Wolfsberg Barbecue and Late night swimming
.
Session
Topic 2: Intra- and Intercellular Signaling
Chairs: Martin Pruschy & Davide Sinat
08:00-08:30
Invited Lecture 1
Sonia Rocha, Liverpool, UK
Molecular oxygen is a potent signaling molecule, lessons from chromatin analysis
08:30-09:00
Invited Lecture 2
Claus Sørensen, Copenhagen, DK
Self-inflicted DNA breaks allow cancer cell escape from growth limits imposed by genotoxic stress
09:00-11:00
Coffee Break / Poster Session Topic II (Poster numbers PII.1-PII.28)
.
11:00-12:00
Proffered Paper Talks
.
11:00 - 11:20
Charles Fouillade, Paris, FR
An interactive single cell atlas of the lung responses to radiation injury
11.20 - 11:40
Florian Wisdorfer, Essen, GE
The role of Neuropilin-1 as therapeutic target in radiation-induced lung fibrosis
11:40 - 12:00
Gosse Adema, Nijmegen, NL
cGAS localization and activation: a guide towards effective combination of RT and Immunotherapy?
12:15 - 13:15
Lunch
_
Session 2
Topic 3: Microenvironment
Chairs: Ludwig Dubois & Hala Awada
13:30-14:00
Invited Lecture 1
Ester Hammond, Oxford, UK
Hypoxia-induced ROS contribute to both replication and transcriptional stress independently of DNA damage
14:00-14:30
Invited Lecture 2
Arne Östmann, Stockholm, SE
Novel subsets of cancer-associated fibroblasts linked to prognosis, response to treatment and immune surveillance
14:30-16:30
Coffee Break / Poster Session Topic III (Poster numbers PIII.1-PIII.24)
.
16:30-17:30
Proffered Paper Talks
.
16:30-16:50
Irma Telarovic, Zurich, CH
Delayed tumor draining lymph node irradiation to maximize the treatment benefit of radiotherapy - immunotherapy
16:50 - 17:10
Sandeep Burma, San Antonio, US
Radiation-induced senescence as a driver of glioblastoma recurrence
17:10 - 17:30
Marianne Koritzinsky, Toronto, CA
Targeting redox homeostasis to reprogram the tumor microenvironment in pancreatic cancer
18:30 - 19:30
WOslo Cup
.
20:00
WOslo Dinner
.
Session 4
Topic 4: Novel Therapies and Biomarkers
Chairs: Heidi Lyng & Kateryna Onyshchenko
08:00 - 08:30
Invited Lecture 1
Fernanda Herrera, Lausanne, CH
Overcoming immune resistance with radiation therapy
8:30-9:00
Invited Lecture 2
Pierre Montay-Gruel, Antwerp, BE
FLASH Radiotherapy: a radiobiology point of view on the FLASH effect
09:00-11:00
Coffee Break / Poster Session Topic IV (Poster numbers PIV.1-PIV.27)
.
11:00-12:00
Proffered Paper Talks
.
11:00-11:20
Ala Yaromina, Maastricht, NL
Impact of LET on tumor response in vivo: potential cooperativity with immunotherapy
11:20-11:40
Randall Kimple, Wisconsin, US
First in human study of autologous MSC(M) for the treatment of radiation-induced xerostomia
11:40-12:00
Mechthild Krause, Dresden, GE
Biomarkers for radio(chemo)therapy in patient HNSCC and in xenografts are similar: clinical validation
12:00-12:25
Award Ceremony
Wolfsberg Poster Awards
12:25-12:30
Closing Remarks
.
12:30-13:15
Lunch
.
13:30
Bus Departure to Oslo Airport
.